根据名称进行药物检索

Cardizem CD 与 Sandimmune (Cyclosporine Oral Solution)

Cardizem CD 与 Sandimmune (Cyclosporine Oral Solution)互相作用以及同时服用的可能性。

检测结果:

Cardizem CD <> Sandimmune (Cyclosporine Oral Solution)

现实性: 24.04.2023 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

使用硫一起孢菌素，可能是有害的肾脏。症状的肾脏损坏包括肿胀，重量增益，感觉，呼吸短促，嗜睡，混乱，情绪变化，增加的口渴、食欲丧失、恶心和呕吐，疼痛在你后背下，排尿或多或少比平常或没有。联系您的医生，如果你还会遇到腹泻、肌肉疼痛或无力、头晕、疲劳或头痛的问题。如果你采取这两种药物在一起，告诉医生，如果你有任何的这些症状。你可能需要的剂量调整或特别的测试安全地使用这些药物在一起。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

监视器：硫可能会抑制CYP450 3A4肝新陈代谢的环孢菌素。槽和稳定状态的级别和肾毒性的风险可能会增加。

管理：Cyclosporine的水平和肾功能应该进行监测，并且剂量应根据需要进行调整，并在适当的治疗。其他钙通道阻断剂，具有较小影响孢菌素的新陈代谢也可以考虑作为替代办法(例如，地平,伊拉地平、硝苯地平，尼群地).

来源

Oppenheimer F, Alcaraz A, Manalich M, et al "Influence of the calcium blocker diltiazem on the prevention of acute renal failure after renal transplantation." Transplant Proc 24 (1992): 50-1
"Product Information. Sandimmune (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Brockmoller J, Neumayer HH, Wagner K, et al "Pharmacokinetic interaction between cyclosporin and diltiazem." Eur J Clin Pharmacol 38 (1990): 237-42
Puig JM, Lloveras J, Oliveras A, et al "Usefulness of diltiazem in reducing the incidence of acute tubular necrosis in Euro-Collins-preserved cadaveric renal grafts." Transplant Proc 23 (1991): 2368-9
Kunzendorf U, Walz G, Brockmoeller J, et al "Effects of diltiazem upon metabolism and immunosuppressive action of cyclosporine in kidney graft recipients." Transplantation 52 (1991): 280-4
Pochet JM, Pirson Y "Cyclosporin-diltiazem interaction." Lancet 1 (1986): 979
Sketris IS, Methot ME, Nicol D, Belitsky, Knox MG "Effect of calcium-channel blockers on cyclosporine clearance and use in renal transplant patients." Ann Pharmacother 28 (1994): 1227-31
Yee GC, McGuire TR "Pharmacokinetic drug interactions with cyclosporin (part II)." Clin Pharmacokinet 19 (1990): 400-15
Wahlberg J, Hanas E, Bergstrom C, et al "Diltiazem treatment with reduced dose of cyclosporine in renal transplant recipients." Transplant Proc 24 (1992): 311-2
Macdonald P, Keogh A, Connell J, Harvison A, Richens D, Spratt P "Diltiazem co-administration reduces cyclosporine toxicity after heart transplantation: a prospective randomised study." Transplant Proc 24 (1992): 2259-62
Grino JM, Sabate I, Castelao AM, Alsina J "Influence of diltiazem on cyclosporin clearance." Lancet 1 (1986): 1387
Neumayer HH, Wagner K "Diltiazem and economic use of cyclosporin." Lancet 2 (1986): 523
Foradori A, Mezzano S, Videla C, Pefaur J, Elberg A "Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazole in stable adult kidney transplants." Transplant Proc 30 (1998): 1685-7
Jacobs U, Klein B, Klehr HU "Cumulative side effects of cyclosporine and ca antagonists: hypergalactinemia, mastadenoma, and gynecomastia." Transplant Proc 26 (1994): 3122
Alcaraz A, Oppenheimer F, Talbot-Wright R, et al "Effect of diltiazem in the prevention of acute tubular necrosis, acute rejection, and cyclosporine levels." Transplant Proc 23 (1991): 2383-4
Sabate I, Grino JM, Castelao AM, et al "Cyclosporin-diltiazem interaction: comparison of cyclosporin levels measured with two monoclonal antibodies." Transplant Proc 21 (1989): 1460-1
Morris RG, Jones TE "Diltiazem disposition and metabolism in recipients of renal transplants." Therapeutic Drug Monitoring 20 (1998): 365-70
Cockburn IT, Krupp P "An appraisal of drug interactions with sandimmun." Transplant Proc 21 (1989): 3845-50

Cardizem CD

非专利名称: diltiazem

品牌: Cardizem CD, Cartia XT, Dilt-XR, Diltia XT, Taztia XT, Tiazac, Cardizem, Dilacor XR, Dilt-CD, Diltzac, Matzim LA, Tiazac, Cardizem LA, Tiazac Extended Release Capsules

同义词: 无

Cardizem CD是什么？