Equetro 与 Griseofulvin Ultramicrosize Tablets
Equetro 与 Griseofulvin Ultramicrosize Tablets互相作用以及同时服用的可能性。
在该服务的官方手册中,已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果,或起到良好效果。具体联合用药问题,需遵从医嘱。
用户:采用灰黄霉素一起卡马西平可能下降的影响的卡马西平。 联系您的医生如果您的状况改变或者如果你的经验癫痫发作和其他精神状态的变化。 如果你的医生,并规定这些药物在一起,可能需要的剂量调整或特别的测试安全地使用这两种药物。 重要的是要告诉你的医生关于所有其他药物的使用,包括维生素和草药。 不停止使用任何药物,没有第一个说你的医生。
医界专家:监视器:共同给予与的诱导剂的CYP450 3A4可能会降低的等离子浓度和药理效果的卡马西平,这主要是代谢的同工酶. 相互作用已经报告了与已知的CYP450 3A4诱导物,例如苯巴比妥、苯妥英、和扑米酮.
管理:药理效果与血清浓度的卡马西平,应该监测更密切地时CYP450 3A4诱加入或撤离治疗和卡马西平的剂量进行调整是必要的。
- "Product Information. Tegretol (carbamazepine)." Novartis Pharmaceuticals, East Hanover, NJ.
- Tomson T, Spina E, Wedlund JE "Minor additive inducing effects of phenobarbital on carbamazepine clearance in patients on combined carbamazepine-phenytoin therapy." Ther Drug Monit 9 (1987): 117-9
- Spina E, Martines C, Fazio A, Trio R, Pisani F, Tomson T "Effect of phenobarbital on the pharmacokinetics of carbamazepine-10, 11-epoxide, an active metabolite of carbamazepine." Ther Drug Monit 13 (1991): 109-12
- Zielinski JJ, Haidukewych D "Dual effects of carbamazepine-phenytoin interaction." Ther Drug Monit 9 (1987): 21-3
- Eichelbaum M, Kothe KW, Hoffmann F, von Unruh GE "Kinetics and metabolism of carbamazepine during combined antiepileptic drug therapy." Clin Pharmacol Ther 26 (1979): 366-71
- Liu H, Delgado MR "Interactions of phenobarbital and phenytoin with carbamazepine and its metabolites' concentrations, concentration ratios, and level dose ratios in epileptic children." Epilepsia 36 (1995): 249-54
- Ramsay RE, McManus DQ, Guterman A, et al "Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy." Ther Drug Monit 12 (1990): 235-41
- Benetello P, Furlanut M "Primidone-carbamazepine interaction: clinical consequences." Int J Clin Pharmacol Res 7 (1987): 165-8
非专利名称: carbamazepine
品牌: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR
同义词: 无
非专利名称: griseofulvin
品牌: Grifulvin V, Fulvicin P/G, Fulvicin U/F, Gris-PEG, Grisactin Ultra, Grisactin 250, Grisactin 500, Griseofulicin, Griseofulvic
同义词: Griseofulvin
在药物相容性与互相作用的检测过程中使用下列的信息来源:Drugs.com, Rxlist.com, Webmd.com, Medscape.com。
- Equetro-Guaiatussin AC
- Equetro-Guaifen DAC
- Equetro-Guaifenesin AC Liquid
- Equetro-Guaifenesin and Codeine
- Equetro-Guaifenesin and Dextromethorphan Capsules and Tablets
- Equetro-Guaifenesin and Dextromethorphan Extended-Release Tablets
- Griseofulvin Ultramicrosize Tablets-Equilizer Gas Relief
- Griseofulvin Ultramicrosize Tablets-Equipto-Amitriptyline Cream
- Griseofulvin Ultramicrosize Tablets-Eravacycline
- Griseofulvin Ultramicrosize Tablets-Eravacycline Dihydrochloride
- Griseofulvin Ultramicrosize Tablets-Eravacycline Intravenous
- Griseofulvin Ultramicrosize Tablets-Eraxis