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Jantoven 与 Tri-Vitamin Drops with Iron and Fluoride

Jantoven 与 Tri-Vitamin Drops with Iron and Fluoride互相作用以及同时服用的可能性。

检测结果:

Jantoven <> Tri-Vitamin Drops with Iron and Fluoride

现实性: 10.09.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

很少、补充维生素含有维生素K可能会降低效力的华法林. 这可能是更可能发生在个人水平低维生素K在他们的血液。在使用任何维生素补充，你应该检查一下标签，以确保它不含有维生素K.如果是这样，让你的医生之前知道你开始使用它。你可能需要更多的频繁监视你的印度卢比开始之后补充或随时停止和进行适当的调整在你的剂量，如果有必要的。重要的是要告诉你的医生关于所有其他药物的使用，包括其他营养补充剂和药材。不停止使用任何药物，没有第一个说你的医生。

医界专家:

监视器：多种维生素的制剂中含有维生素K可以对抗hypoprothrombinemic效果的口服抗凝血剂在某些患者。维生素K1在其活动，减少形式作为一个辅助因素产生的功能凝固因素，在这期间它变成氧化。这是重新激活中的一个过程被抑制通过口服抗凝血剂，从而摄入的额外维生素K通过补充或饮食可以逆转的行动的口服抗凝血剂。虽然量的维生素K在柜台多种维生素的筹备工作通常是低的剂量，认为影响的抗凝中，有的已经分离的情况报告的患者中稳定在华法林的印度卢比下降了以下发起的多种维生素补充和返回的治疗水平在停止多种维生素。增加了在华法林的剂量都必须在一些情况下，当多种维生素是继续进行。一个病人的药物剂量是增加的开发了一个包膜下血肿中她的右肾两个星期后，她停止了多种维生素而不通知她的医生。她的印度卢比的是13.2和她处理与维生素K和新鲜冰冻血浆。这是可能的，患者低维生素K状况可能特别容易受到相互作用。调查显示，维生素K缺乏症会导致过分敏感，甚至少增加了维生素K摄入量。在一项研究中华法林的-稳定患者被给予一个多种维生素片剂含有25毫克维生素K1每日4个星期，亚治疗INRs发生在9 9患者低维生素K1水平(<1.5微克/升)，只有1的7名患者正常的维生素K1水平(>4.5微克/升)。印度卢比减少一个中间值的0.51和华法林的剂量必须增加了5.3％，在患者与低维生素K1水平，而印度卢比和华法林的剂量没有显着变化，在患者正常的维生素K1的水平。普遍缺乏维生素K可能很小，但意义重大的抗凝人口。在调查的179个连续的门诊患者在稳定药物治疗参加一个抗凝诊所，22(12.3%)被发现有维生素K1缺乏(<0.1纳克/毫升)。

管理：潜在的多种维生素补充剂中含有的甚至低水平的维生素K影响的抗凝应该得到承认。特别是，老年人和/或营养不良的患者可能需要更经常监测印度卢比以下的启动或中止的多种维生素补充剂和抗凝血剂量调整是必要的。

来源

Ducharlet KN, Katz B, Leung S "Multivitamin supplement interaction with warfarin therapy." Australas J Ageing 30 (2011): 41-2
Kumik D, Lubetsky A, Loebstein R, Almog S, Halkin H "Multivitamin supplements may affect warfarin anticoagulation in susceptible patients." Ann Pharmacother 37 (2003): 1603-6
Kurnik D, Loebstein R, Rabinovitz H, Austerweil N, Halkin H, Almog S "Over-the-counter vitamin K1-containing multivitamin supplements disrupt warfarin anticoagulation in vitamin K1-depleted patients. A prospective, controlled trial." Thromb Haemost 92 (2004): 1018-24

Jantoven

非专利名称: warfarin

品牌: Coumadin, Jantoven

同义词: 无

Jantoven是什么？

Tri-Vitamin Drops with Iron and Fluoride

非专利名称: multivitamin with iron and fluoride

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同义词: 无

Tri-Vitamin Drops with Iron and Fluoride是什么？

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