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Acetazolamide Sustained-Release Capsules 与 Aspirin and Omeprazole Tablets

Acetazolamide Sustained-Release Capsules 与 Aspirin and Omeprazole Tablets互相作用以及同时服用的可能性。

检测结果:
Acetazolamide Sustained-Release Capsules <> Aspirin and Omeprazole Tablets
现实性: 06.07.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中,已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果,或起到良好效果。具体联合用药问题,需遵从医嘱。

用户:

问问你的医生之前使用胺一起与阿司匹林。 这可能会导致耳鸣、头痛、恶心、呕吐、眩晕、混乱的、幻觉,呼吸急促、发烧、扣押(抽搐),或者昏迷。 如果你的医生,并规定这些药物在一起,可能需要的剂量调整或特别的测试,以安全地把这两种药物。 重要的是要告诉你的医生关于所有其他药物的使用,包括维生素和草药。 不停止使用任何药物,没有第一个说你的医生。

医界专家:

一般避免结合的大剂量的水杨酸和口头碳酸酐酶抑制剂(蔡)可很少导致在严重的代谢性酸中毒和/或水杨酸的毒性。 该机制是未知的,但可能涉及水杨酸盐引起的流离失所问题的蔡从血浆中的蛋白质结合点和减少的肾脏清,或蔡诱发的等离子体pH值的变化导致增加数量的工会的水杨酸盐进入中枢神经系统。 昏迷和死亡的报道。 虽然这没有被报告的眼蔡,临床医生应该考虑的可能性相互作用与这些代理,还。

管理:在一般情况下,伴随使用的风湿剂量的水杨酸和口腔蔡不建议。 如果合用是必要的,仔细监测患者的精神状态和酸碱平衡,强烈建议。 病人应当建议及时通知他们的医生如果他们经历的症状,如无生气、耳鸣,混乱、恶心、呕吐,或过度换气。

来源
  • Sweeney KR, Chapron DJ, Brandt JL, Gomolin IH, Feig PU, Kramer PA "Toxic interaction between acetazolamide and salicylate: case reports and a pharmacokinetic explanation." Clin Pharmacol Ther 40 (1986): 518-24
  • Sweeney KR, Chapron DJ, Kramer PA "Effect of salicylate on serum protein binding and red blood cell uptake of acetazolamide in vitro." J Pharm Sci 77 (1988): 751-6
  • Cowan RA, Hartnell GG, Lowdell CP, Baird IM, Leak AM "Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function." Br Med J (Clin Res Ed) 289 (1984): 347-8
  • Rousseau P, Fuentevilla-Clifton A "Acetazolamide and salicylate interaction in the elderly: a case report." J Am Geriatr Soc 41 (1993): 868-9
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • "Product Information. Diamox (acetazolamide)." Lederle Laboratories, Wayne, NJ.
  • Cowan RA, Hartnell GG, Lowdell CP, Baird IM, Leak AM "Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function." Br Med J (Clin Res Ed) 289 (1984): 347-8
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Azopt (brinzolamide ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
  • Sweeney KR, Chapron DJ, Brandt JL, Gomolin IH, Feig PU, Kramer PA "Toxic interaction between acetazolamide and salicylate: case reports and a pharmacokinetic explanation." Clin Pharmacol Ther 40 (1986): 518-24
  • Sweeney KR, Chapron DJ, Antal EJ, Kramer PA "Differential effects of flurbiprofen and aspirin on acetazolamide disposition in humans." Br J Clin Pharmacol 27 (1989): 866-9
  • "Product Information. Trusopt (dorzolamide ophthalmic)." Merck & Co, Inc, West Point, PA.
  • Anderson CJ, Kaufman PL, Sturm RJ "Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin." Am J Ophthalmol 86 (1978): 516-9
  • Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
  • Favre L, Vallotton MB "Relationship of renal prostaglandins to three diuretics." Prostaglandins Leukot Med 14 (1984): 313-9
  • Cowan RA, Hartnell GG, Lowdell CP, Baird IM, Leak AM "Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function." Br Med J (Clin Res Ed) 289 (1984): 347-8
Acetazolamide Sustained-Release Capsules

非专利名称: acetazolamide

品牌: Diamox, Diamox Sequels

同义词: Acetazolamide, AcetaZOLAMIDE

Aspirin and Omeprazole Tablets

非专利名称: aspirin / omeprazole

品牌: Yosprala

同义词: Aspirin and omeprazole, Aspirin and Omeprazole

在药物相容性与互相作用的检测过程中使用下列的信息来源:Drugs.com, Rxlist.com, Webmd.com, Medscape.com。