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Articaine and epinephrine 与 Istalol

Articaine and epinephrine 与 Istalol互相作用以及同时服用的可能性。

检测结果:

Articaine and epinephrine <> Istalol

现实性: 10.06.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

Β受体阻滞剂喜欢吗洛尔眼可以减少影响的肾上腺素。如果你有用吗洛尔眼科，你可以不回应，以及肾上腺素当给予治疗紧急情况等冲击或严重过敏的反应。另外，结合可能会导致严重的血压高和降低心率。你的医疗保健提供者应该始终被告知，如果你正在接受或最近收到的、β受体阻滞剂治疗。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

密切监测:Noncardioselective β受体阻滞剂可以大大增强加压反应肾上腺素。该机制涉及的封锁的beta-2肾上腺素受体外周血管系统，导致在无人反对，α-肾上腺素效应的肾上腺素，负责血管收缩。严重的血压伴随心动过缓报告了患者与被处理的一个noncardioselective阻滞剂喜欢这种药物或萘羟心安之前收到肾上腺素。在罕见的情况下，心脏病和中风时有发生。这种相互作用还没有报道有cardioselective的β受体阻断剂，这通常具有影响beta-2肾上腺素受体在治疗的剂量。在研究的高血压患者，处理与这种药物是相关的大量增加血压和末稍血管抗性和减少心率和前臂血流在应对肾上腺素的管理，而药物只有轻微的影响肾上腺素诱发心血管变化的比较来安慰剂。同样，在24个健康的主题处理的与这种药物、阿替，或者安慰剂对于前一星期肾上腺素的管理，意味着动脉压力和牛的血管抗性增加显着的萘羟心安组而不是在洛基，并标志着缓也发生在前者而不是后一组。理论上，相互作用，也可能发生与noncardioselective阻滞剂眼的筹备工作，因为它们可以系统地吸收，并可以产生显着临床的系统性影响，甚至在低或无法检测的血浆水平。

密切监测：Β受体阻滞剂可减轻应对肾上腺素在处理的过敏反应。 Noncardioselective β受体阻滞剂，特别是可对抗的支气管扩张影响的肾上腺素的阻beta-2肾上腺素受体在平滑肌肉支气管树。所有的β受体阻滞剂可以对抗的cardiostimulatory影响的肾上腺素的阻β-1肾上腺素受体中心。一些调查人员建议使用的β受体阻滞剂本身是相关的发病率增加和严重的过敏反应由于调制腺苷酸环化酶，这可能影响释放anaphylactogenic调解员。然而，数据是有限的，相互矛盾的。

管理：极端谨慎，并密切监测心血管状态是指出当肾上腺素是给予治疗的患者noncardioselective的β受体阻滞剂。一剂用量减少的肾上腺素可能是必要的。撤出的β受体阻滞剂麻醉前可能会增加风险的心肌局部缺血和不建议。相互作用预计不会发生局部麻醉剂中使用的牙科手术，含有浓度很低的肾上腺素。

来源

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