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Aspirin 与 Pegaspargase Intramuscular, Intravenous

Aspirin 与 Pegaspargase Intramuscular, Intravenous互相作用以及同时服用的可能性。

检测结果:

Aspirin <> Pegaspargase Intramuscular, Intravenous

现实性: 03.09.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

使用阿司匹林一起与培门可以因为你流血更容易。叫你的医生及时如果你有任何不寻常或出血瘀伤、呕吐、血液在你的尿液或凳子、头疼、头晕、或弱点。你可能需要的剂量调整或特别的测试，以安全地使用这两种药物。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

监视器：药物治疗可能导致不平衡，在凝结的因素诱发的病人的出血或血栓形成。理论上，同时使用抗凝血剂和药物的可能增加出血的风险。出血3级和以上和CNS出血已经观察到的与药物治疗。然而，严重血栓事件还报告了与使用药物. 一些调查人员建议，抗凝血剂可用于预防与药物对于防止血栓的事件。

管理：混凝参数应当监测在基线和定期伴随的治疗药物和抗凝血剂，如：肝素，达莫，阿司匹林和非甾体抗炎药物。患者应立即报告任何迹象和症状的流血。

来源

Caruso V, Iacoviello L, Di Castelnuovo A, et.al "Thrombotic complications in childhood acute lymphoblastic leukemia: a meta-analysis of 17 prospective studies comprising 1752 pediatric patients." Blood 108 (2006): 2216-22
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Duarte X, Esteves S, Neto AM, Pereira F "Incidence and risk factors for central nervous system thrombosis in paediatric acute lymphoblastic leukaemia during intensive asparaginase treatment: a single-centre study." Br J Haematol 174 (2016): 280-91
Cerner Multum, Inc. "Australian Product Information." O 0
Kieslich M, Porto L, Lanfermann H, Jacobi G, Schwabe D, Bohles H "Cerebrovascular complications of L-asparaginase in the therapy of acute lymphoblastic leukemia." J Pediatr Hematol Oncol 25 (2003): 484-7
"Product Information. Erwinaze (asparaginase Erwinia chrysanthemi)." EUSA Pharma, Newtown, PA.
"Product Information. Oncaspar (pegaspargase)." Rhone-Poulenc Rorer, Collegeville, PA.
Grace RF, DeAngelo DJ, Stevenson KE, et.al "The use of prophylactic anticoagulation during induction and consolidation chemotherapy in adults with acute lymphoblastic leukemia." J Thromb Thrombolysis 45 (2018): 306-14
Mitchell L, Andrew M, Hanna K, et.al "Trend to efficacy and safety using antithrombin concentrate in prevention of thrombosis in children receiving l-asparaginase for acute lymphoblastic leukemia. Results of the PAARKA study." Thromb Haemost 90 (2003): 235-44
Truelove E, Fielding AK, Hunt BJ "The coagulopathy and thrombotic risk associated with L-asparaginase treatment in adults with acute lymphoblastic leukaemia." Leukemia 27 (2013): 553-9
"Product Information. Asparlas (calaspargase pegol)." Servier, Boston, MA.
Elice F, Rodeghiero F "Hematologic malignancies and thrombosis." Thromb Res 129 (2012): 360-6
"Product Information. Elspar (asparaginase)." Merck & Co, Inc, West Point, PA.

Aspirin

非专利名称: aspirin

品牌: Arthritis Pain, Aspir 81, Aspir-Low, Bayer Childrens Aspirin, Durlaza, Ecotrin, Ecpirin, Fasprin, Halfprin, Miniprin, Aspiritab, Bayer, Bayer Low Strength, Bayer Children's, St. Joseph 81 mg Adult

同义词: 无

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