根据名称进行药物检索

Betimol 与 Tiotropium and Olodaterol

Betimol 与 Tiotropium and Olodaterol互相作用以及同时服用的可能性。

检测结果:

Betimol <> Tiotropium and Olodaterol

现实性: 02.05.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

使用吗洛尔眼科与氢化可的松可能会减少福利的这两种药物，因为它们具有相对的效果在身体。此外，吗洛尔眼科有时会导致收缩的航空公司，这可能会恶化你的呼吸问题或触发严重的哮喘的攻击。吗洛尔眼科通常不建议如果你有哮喘、一个历史记录的哮喘，或严重慢性阻塞性肺部疾病(COPD)。谈谈你的医生如果你有任何疑问或关切的问题。你的医生可以规定替代办法，不相互作用或者很少进行互动。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

一般避免：Β受体阻滞剂可对抗的影响，β-2支气管扩张剂肾上腺素和沉淀物的急性的，威胁生命支气管痉挛在患有哮喘或其他性呼吸道阻塞性疾病。该机制涉及增加道阻力和降低支气管扩张，由于封锁的beta-2肾上腺素受体。相互作用，也可能发生与眼科学应用的β受体阻断剂，这是系统地吸收，并可以产生显着临床的系统性影响，甚至在低或无法检测的血浆水平。由于反对影响beta-2肾上腺素受体，这种药物具有被用于治疗的沙丁胺醇过量。同样，β-2肾上腺素激动剂，可能会干扰药理作用的β受体阻滞剂。

管理：伴随使用的β-2肾上腺素能支气管扩张剂的β受体阻断剂，其中包括眼科的制剂，一般应当是可以避免的。如果合用是必需的，cardioselective阻滞剂(例如，醋丁洛尔、阿替,倍他洛尔、比索洛尔、美托洛尔、奈必洛尔)是通常的首选。尽管如此，谨慎建议，并呼吸状态，应密切监测，作为cardioselectivity不是绝对的和更大的剂量β-1中选择剂可能造成一些相同的风险作为非选择性剂。在一般情况下，非选择性的β受体阻滞剂被认为是禁忌的患者的性阻塞性气管疾病。

来源

Craig TJ "Drugs to be used with caution in patients with asthma." Am Fam Physician 54 (1996): 947-53
Chafin CC, Soberman JE, Demirkan K, Self T "Beta-blockers after myocardial infarction: Do benefits ever outweigh risks in asthma?." Cardiology 92 (1999): 99-105
Chodosh S, Tuck J, Blasucci DJ "The effects of dilevalol, metoprolol, and placebo on ventilatory function in asthmatics." J Cardiovasc Pharmacol 11 (1988): s18-24
Hollenberg NK "The role of beta-blockers as a cornerstone of cardiovascular therapy." Am J Hypertens 18(12 Pt 2) (2005): 165S-168S
Baselli LM, Oswald MA, Nashelsky JM "Do beta-blockers worsen respiratory status for patients with COPD?" J Fam Pract 54 (2005): 472-3
"Product Information. Breo Ellipta (fluticasone-vilanterol)." GlaxoSmithKline, Research Triangle Park, NC.
"Product Information. Corgard (nadolol)." Bristol-Myers Squibb, Princeton, NJ.
Sheppard D, DiStefano S, Byrd RC, Eschenbacher WL, Bell V, Steck J, Laddu A "Effects of esmolol on airway function in patients with asthma." J Clin Pharmacol 26 (1986): 169-74
Ruffin RE, Frith PA, Anderton RC, Kumana CR, Newhouse MT, Hargreave FE "Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation." Clin Pharmacol Ther 25 (1979): 536-40
"Product Information. Blocadren (timolol)." Merck & Co, Inc, West Point, PA.
"Product Information. Betagan Liquifilm (levobunolol)." Allergan Inc, Irvine, CA.
Salpeter SS, Ormiston T, Salpeter E, Poole P, Cates D "Cardioselective beta-blockers for chronic obstructive pulmonary disease." Cochrane Database Syst Rev 2 (2002): CD0003566
Dunn TL, Gerber MJ, Shen AS, Fernandez E, Iseman MD, Cherniak RM "The effect of topical ophthalmic instillation of timolol and betaxolol on lung function in asthmatic subjects." Am Rev Respir Dis 133 (1986): 264-8
Falliers CJ, Vincent ME, Medakovic M "Effect of single doses of labetalol, metoprolol, and placebo on ventilatory function in patients with bronchial asthma: interaction with isoproterenol." J Asthma 23 (1986): 251-60
Brooks AM, Burden JG, Gillies WE "The significance of reactions to betaxolol reported by patients." Aust N Z J Ophthalmol 17 (1989): 353-5
Brooks AM, Gillies WE "Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects." Drugs Aging 2 (1992): 208-21
Ashrafian H, Violaris AG "Beta-blocker therapy of cardiovascular diseases in patients with bronchial asthma or COPD: the pro viewpoint." Prim Care Respir J 14 (2005): 236-41
Bloom B, Chalmers PC, Danker PR, Kumar S, Sheikh F "Cardiovascular collapse and refractory bronchospasm following administration of vancomycin, esmolol, and heparin." J Cardiothorac Anesth 3 (1989): 748-51
van der Woude HJ, Zaagsma J, Postma DS, Winter TH, van Hulst M, Aalbers R "Detrimental effects of beta-blockers in COPD: a concern for nonselective beta-blockers." Chest 127 (2005): 818-24
"Product Information. Striverdi Respimat (olodaterol)." Boehringer Ingelheim, Ridgefield, CT.
Gold MR, Dec GW, Cocca-Spofford D, Thompson BT "Esmolol and ventilatory function in cardiac patients with COPD." Chest 100 (1991): 1215-8
Mooss AN, Hilleman DE, Mohiuddin SM, Hunter CB "Safety of esmolol in patients with acute myocardial infarction treated with thrombolytic therapy who had relative contraindications to beta-blocker therapy." Ann Pharmacother 28 (1994): 701-3
"Product Information. Normodyne (labetalol)." Schering Laboratories, Kenilworth, NJ.
Cazzola M, Noschese P, D'Amato M, D'Amato G "Comparison of the effects of single oral doses of nebivolol and celiprolol on airways in patients with mild asthma." Chest 118 (2000): 1322-6
Tafreshi MJ, Weinacker AB "Beta-adrenergic-blocking agents in broncospastic diseases: a therapeutic dilemma." Pharmacotherapy 19 (1999): 974-8
"Product Information. Arcapta Neohaler (indacaterol)." Novartis Pharmaceuticals, East Hanover, NJ.
Rasch D, Holt J, Wilson M, Smith RB "Bronchospasm following intraocular injection of acetylcholine in a patient taking metoprolol." Anesthesiology 59 (1983): 583-5
Salpeter SR, Ormiston TM, Salpeter EE "Cardioselective beta-blockers in patients with reactive airway disease: a meta-analysis." Ann Intern Med 137 (2002): 715-25
"Product Information. Brovana (arformoterol)." Sepracor Inc, Marlborough, MA.
Herschman Z, Kaufman B "Complications arising from the use of ophthalmologic medications in an intensive care unit patient." N Y State J Med 89 (1989): 537-8
Macquin-Mavier I, Roudot-Thorval F, Clerici C, George C, Harf A "Comparative effects of bisoprolol and acebutolol in smokers with airway obstruction." Br J Clin Pharmacol 26 (1988): 279-84
Thiringer G, Svedmyr N "Interaction of orally administered metoprolol, practolol and propranolol with isoprenaline in asthmatics." Eur J Clin Pharmacol 10 (1976): 163-70
"Product Information. Coreg (carvedilol)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Volmax (albuterol)" Muro Pharmaceuticals Inc, Tewksbury, MA.
"Product Information. OptiPranolol (metipranolol)." Bausch and Lomb, Tampa, FL.
Cazzola M, Noschese P, D'Amato G, Matera MG "The pharmacologic treatment of uncomplicated arterial hypertension in patients with airway dysfunction." Chest 121 (2002): 230-41
De Bono G, Kaye CM, Roland E, Summers AJ "Acebutolol: ten years of experience." Am Heart J 109 (1985): 1211-3
"Product Information. Inderal (propranolol)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Timoptic (timolol ophthalmic)." Merck & Co, Inc, West Point, PA.
Johnsson G, Svedmyr N, Thiringer G "Effects of intravenous propranolol and metoprolol and their interaction with isoprenaline on pulmonary function, heart rate and blood pressure in asthmatics." Eur J Clin Pharmacol 8 (1975): 175-80