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Eskalith-CR 与 Zorvolex

Eskalith-CR 与 Zorvolex互相作用以及同时服用的可能性。

检测结果:

Eskalith-CR <> Zorvolex

现实性: 16.08.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

芬酸可能会显着增加的血液水平的锂在一些患者造成的锂中毒。谈谈你的医生如果你有任何疑问或关切的问题。你的医生可以规定替代品，不进行互动，或者可能需要一剂量的调整或更频繁的监测安全地使用这两种药物。让你的医生知道，如果你遇到嗜睡头晕、腹泻、呕吐、肌肉软弱，肌肉不协调、颤抖、视力模糊，言犹在耳，过度的渴望，和/或增加的排尿，因为可以将这些症状的过锂水平。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

密切监测:共同给予与非甾体抗炎药(非甾体抗炎药)可以增加血清锂水平，并促使毒性在一些患者。的确切机制的相互作用是未知的，但是认为涉及抑制肾前列腺素的合成药物，导致在下降肾脏中的血流和锂排泄。已经有众多的公布报告的锂毒性，包括严重的情况下，下面所介绍的各种非甾体抗炎药，包括双氯、布洛芬、美辛，酮咯酸、甲灭酸、吡罗昔康和COX-2抑制剂。然而，药物动力学研究中已经有点不一致，没有重大影响的报告benoxaprofen和酸，而高达到58%增加，血清中的锂级报告对于消炎痛。两者降低血清浓度的锂和没有效果已经报告舒和阿司匹林。相互作用显然是受到标interpatient的可变性。

管理：谨慎建议当锂同时使用与非甾体抗炎药. 患者应该有血清锂水平检查，每4到5天之后开始一个非甾体直到的程度的任何潜在的相互作用可以进行评估。减少锂剂量，可能需要在一些情况。病人应被告知寻求医疗注意，如果他们遇到潜在的迹象和症状的锂毒性，例如嗜睡头晕、混乱、弱点、共济失调、震颤、耳鸣，视力模糊、呕吐、腹泻、渴望，并增加的排尿。

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