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Giltuss 与 Zyvox (Linezolid Suspension)

Giltuss 与 Zyvox (Linezolid Suspension)互相作用以及同时服用的可能性。

检测结果:

Giltuss <> Zyvox (Linezolid Suspension)

现实性: 21.07.2023 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

使用美沙芬一起与利奈唑可以增加风险的一个罕见的，但严重的疾病叫做血清素综合症，其中可能包括的症状，如混乱、幻觉、扣押、极端变化血压，心率增加、发烧、多汗、颤抖或颤抖、视力模糊，肌肉痉挛或僵硬、震颤、不协调、胃痉挛、恶心、呕吐、腹泻。严重的情况下可能导致昏迷甚至死亡。你应该立即寻求医疗照顾，如果你经历这些症状的治疗期间。谈谈你的医生如果你有任何疑问或关切的问题。你的医生可以规定替代品，不进行互动，或者可能需要一剂量的调整或更频繁的监测安全地使用这两种药物。不采取任何过咳嗽和感冒药没有咨询一个医疗保健专业人员或检查标签的第一个，因为这些产品可能包含右美沙芬，并可能互动同样有利奈唑. 重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

禁忌:共同给予的右美沙芬与利奈唑可能会增加风险的血清素的综合，一种罕见的，但是严重的和潜在的致命状况的思想导致过度刺激的脑干5-HT1A和2A受体。右美沙芬是一个软弱的血清素再吸收抑制剂的素活性可以增强由单胺氧化酶抑制剂(单胺氧化抑制剂). 严重和致命的反应已有报告说，主要的抗抑郁药的单胺氧化抑制剂. 风险应当低与利奈唑，相对较弱，可逆转的单胺氧化酶抑制剂. 当利奈唑(600毫克的口每12小时6日)和美沙芬(20毫克的口的两倍，4小时的间隔，在天4和6的利奈唑管理)给予14健康的志愿人员，没有精神状态的变化(镇静，性能测试)或自主功能(血压、心律、体温)的中观察到相对于政府的利奈唑或右美沙芬单。转右美沙芬，其主要代谢产物的降低利奈唑，如由一个大约30%的下降在右啡烷峰等离子浓度(C)和系统暴露(AUC)期间共同给予，但意义是未知的。调查人员得出结论，利奈唑可能规定与右美沙芬没有限制。没有发表的报告血清素综合症与同时使用美沙芬，并利奈唑，虽然已知案件已经相关联的单独每一个在共同给予与其他血清素的药剂。英国标签利奈唑描述了一个上市后报告的一个病人遇到的血清素的综合效果期间同时使用美沙芬，解决在终止的这两种药物。

管理：由于风险的血清素综合征，同时使用美沙芬单胺氧化抑制剂和被认为是禁忌，通过制造商的右美沙芬含的产品。如果合用与利奈唑是必需的，患者应当监测对于发展的血清素综合症。症状可能包括精神状态的变化，例如烦躁、改变的意识，混淆，幻觉和昏迷;自主神经功能障碍如性心动过速、热疗、发汗解表、颤抖、血压不稳定，并散瞳;神经肌肉异常比如反射亢进、肌阵挛、震颤、刚性，并共济失调；和胃肠道症状，例如腹部绞痛、恶心、呕吐、腹泻。

来源

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Giltuss

非专利名称: dextromethorphan / guaifenesin / phenylephrine

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