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Guaifenesin, Pseudoephedrine, and Codeine 与 Zoloft

Guaifenesin, Pseudoephedrine, and Codeine 与 Zoloft互相作用以及同时服用的可能性。

检测结果:

Guaifenesin, Pseudoephedrine, and Codeine <> Zoloft

现实性: 17.07.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

舍曲林可以减少有效性的可待因。你可能需要一个剂量的调整，如果你已经把可待因，并开始治疗舍曲林。让你的医生知道如果你的状况改变或者你的经验减少的或不充分的缓解你的症状。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

监视器：药抑制剂的CYP450 2D6可能会干扰的镇痛效果可待因。该机制是减少体内转换的可待因为吗啡的一种新陈代谢的反应介由CYP450 2D6.

管理：可能性的减少或不足痛苦的救济，应该被认为是在患者接受可待因用药物抑制CYP450 2D6. 增加剂量可待因或一个不同的镇痛剂可能必须在患者需要治疗与CYP450 2D6抑制剂。

来源

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Hersh EV, Moore PA "Drug interactions in dentistry: the importance of knowing your CYPs." J Am Dent Assoc 135 (2004): 298-311
Sindrup SH, Arendt-Nielsen L, Brosen K, et al "The effect of quinidine on the analgesic effect of codeine." Eur J Clin Pharmacol 42 (1992): 587-92
Vevelstad M, Pettersen S, Tallaksen C, Brors O "O-demethylation of codeine to morphine inhibited by low-dose levomepromazine." Eur J Clin Pharmacol 65 (2009): 795-801
Sindrup SH, Hofmann U, Asmussen J, Mikus G, Brosen K, Nielsen F, Ingwersen SH, Broen Christensen C "Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake." Eur J Clin Pharmacol 49 (1996): 503-9
Thorn CF, Klein TE, Altman RB "Codeine and morphine pathway." Pharmacogenet Genomics 19 (2009): 556-8
Sindrup SH, Brosen K, Bjerring P, et al. "Codeine increases pain threshold to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine." Clin Pharmacol Ther 49 (1991): 686-93
Caraco Y, Sheller J, Wood JJ "Pharmacogenetic determination of the effects of codeine and prediction of drug interactions." J Pharmacol Exp Ther 278 (1996): 1165-74
Desmeules J, Gascon MP, Dayer P, Magistris M "Impact of environmental and genetic factors on codeine analgesia." Eur J Clin Pharmacol 41 (1991): 23-6
Zhou SF "Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II." Clin Pharmacokinet 48 (2009): 761-804
Desmeules J, Dayer P, Gascon MP, Magistris M "Impact of genetic and environmental factors on codeine analgesia." Clin Pharmacol Ther 45 (1989): 122
Caraco Y, Sheller J, Wood AJJ "Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects." J Pharmacol Exp Ther 290 (1999): 413-22

Guaifenesin, Pseudoephedrine, and Codeine

非专利名称: codeine / guaifenesin / pseudoephedrine

品牌: Ambifed CD, Biotussin DAC, Cheratussin DAC, Guaifen DAC, Lortuss EX, Maxifed-G CD, Nucofed Pediatric Expectorant, Tricode GF, Tusnel C, Virtussin DAC, Virtussin DAC

同义词: Codeine, guaifenesin, and pseudoephedrine

Guaifenesin, Pseudoephedrine, and Codeine是什么？