根据名称进行药物检索

HistaFlex 与 Luminal

HistaFlex 与 Luminal互相作用以及同时服用的可能性。

检测结果:

HistaFlex <> Luminal

现实性: 13.08.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

使用乙酰氨基酚一起用苯巴比妥可改变的影响和对乙酰氨基酚造成严重的负面影响，可能会影响你的肝脏。叫你的医生立即如果你遇到一个热、冷、关节疼痛或肿胀，过度疲劳或无力、不寻常或出血瘀伤、皮疹或搔痒、食欲丧失、恶心、呕吐，或黄皮肤或白你的眼睛。如果你的医生，并规定这些药物在一起，可能需要的剂量调整或特别的测试，以安全地把这两种药物。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

监视器：巴比妥类药物的可能增加的肝脏潜在的对乙酰氨基酚和减少其治疗的效果。该机制可以是相关的加速CYP450新陈代谢对乙酰氨基酚与随之增加，在肝毒性代谢物。这种相互作用是最令人关切的情况下对乙酰氨基酚过量。

管理：监测为改变的有效性和安全性建议。延长使用或高剂量乙酰氨基酚应避免通过病人在巴比妥酸盐治疗。

来源

Wright N, Prescott LF "Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdose." Scott Med J 18 (1973): 56-8
Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J "Paracetamol as a test drug to determine glucuronide formation in man: effects of inducers and of smoking." Eur J Clin Pharmacol 31 (1987): 677-83
Pirotte JH "Apparent potentiation by phenobarbital of hepatotoxicity from small doses of acetaminophen." Ann Intern Med 101 (1984): 403
Douidar SM, Ahmed AE "A novel mechanism for the enhancement of acetaminophen hepatotoxicity by phenobarbital." J Pharmacol Exp Ther 240 (1987): 578-83

HistaFlex

非专利名称: acetaminophen / pyrilamine

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