根据名称进行药物检索

HistaFlex 与 Xatmep

HistaFlex 与 Xatmep互相作用以及同时服用的可能性。

检测结果:

HistaFlex <> Xatmep

现实性: 13.08.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

甲氨蝶呤可能会导致肝脏问题，并利用它与其他药物，也可能影响肝脏中如对乙酰氨基酚可能增加这种风险。你应该避免或限制使用酒精，同时正在处理与这些药物。叫你的医生立即如果你有热、冷、关节疼痛或肿胀、不寻常或出血瘀伤、皮疹、瘙痒，食欲不振、疲劳、恶心、呕吐、腹痛、尿的，苍白的凳子，和/或黄皮肤或眼睛，因为这些可能的迹象和症状的肝脏损伤。谈谈你的医生或药剂师，如果你有任何疑问或关切的问题。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

监视器：共同给予的甲氨蝶呤与其他已知的代理诱导肝毒性可能会加强风险的肝脏损伤。甲氨蝶呤，特别是在较高剂量或与长期治疗，已经与包括急性肝毒性肝炎、慢性纤维化、坏疽、肝硬化、肝酶升高。

管理：危险的肝损伤时，应考虑甲氨蝶呤是使用与其他可能有肝毒性剂(例如，对乙酰氨基酚;醇；雄性激素和合成类固醇;抗结核药；唑抗真菌剂；ACE抑制剂；药(高剂量);双硫;皮素受体拮抗剂；干扰素;内酯和大环内酯类抗生素；激酶抑制剂；环素;非甾体抗炎药；核苷逆转录酶抑制剂；蛋白酶抑制剂；类;磺胺;他;噻唑;托伐普坦;药;齐留通；抗惊厥药如卡马西平，脲, 非尔氨酯和丙戊酸；降低脂质的药物，如非诺贝特，lomitapide,mipomersen、烟酸和汀;草药和营养补充剂，如黑升麻，林，紫草，酮，卡瓦,薄荷油和红曲). 基准和周期性监测的肝功能是建议，而肝活组织检查可能需要在长期使用的甲氨蝶呤。病人应被告知寻求医疗注意，如果他们遇到潜在的迹象和症状的肝毒性，例如发烧、皮疹、瘙痒、厌食症、恶心、呕吐、疲劳，右上象限疼痛、尿的，苍白的凳子，和黄疸。

来源

"Product Information. Methotrexate (methotrexate)." Lederle Laboratories, Wayne, NJ.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

HistaFlex

非专利名称: acetaminophen / pyrilamine

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