Ibuprofen Llysine 与 Zide
Ibuprofen Llysine 与 Zide互相作用以及同时服用的可能性。
在该服务的官方手册中,已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果,或起到良好效果。具体联合用药问题,需遵从医嘱。
用户:之前把氢氯,告诉医生,如果你还用布洛芬。 你可能需要的剂量调整或特别的测试,以便安全地把这两种药物在一起。 如果你收到这个组合多喝水。 血压、肾功能应该受到监测。 重要的是,你告诉你的医疗保健提供者有关的所有其他药物的使用,包括维生素和草药。 不停止使用药物而不首先说你的医生第一次。
医界专家:监视器同时使用非甾体抗炎药(非甾体抗炎药)和利尿剂可能造成不利影响肾功能由于非甾体抑制肾合成前列腺素帮助保持肾灌注于脱水状态。 风险可能会增加患者的饮食钠限制。 同时,低血压效果的利尿剂可能会减少,因为抑制作用的前列腺素可能会导致对抗加压活动,因此,提升血压力。 利钠和利尿剂的影响也可能减少,因为非甾体抗炎药已报告导致钠和水的保留,这可能增加风险的充血性心力衰竭相关的组合。 一项研究表明,在增加的发病率密度的充血性心力衰竭(在55岁以上患者的年龄)从9.3每1 000人年的患者对利尿剂23.3每1 000人年在患者关于两者的利尿剂和非甾体疗法。 非甾体抗炎药也可能增加风险的高血钾与钾利尿剂。
管理:在患者接受两者的利尿剂和非甾体治疗,管理包括避免脱水和仔细监测患者的肾功能和血压力。 如果肾脏功能不足或高血钾的发展,这两种药物应该停止,直到条件进行修正。
- Muller FO, Schall R, Devaal AC, Groenewoud G, Hundt HKL, Middle MV "Influence of meloxicam on furosemide pharmacokinetics and pharmacodynamics in healthy volunteers." Eur J Clin Pharmacol 48 (1995): 247-51
- McCarthy JT, Torres VE, Romero JC, et al "Acute intrinsic renal failure induced by indomethacin." Mayo Clin Proc 57 (1982): 289-96
- Brater DC, Fox WR, Chennavasin P "Interaction studies with bumetanide and furosemide: effects of probenecid and of indomethacin on response to bumetanide in man." J Clin Pharmacol 21 (1981): 647-53
- Allan SG, Knox J, Kerr F "Interaction between diuretics and indomethacin." Br Med J 283 (1981): 1611
- Desaulles E, Schwartz J "A comparative study of the action of frusemide and methyclothiazide on renin release by rat kidney slices and the interaction with indomethacin." Br J Pharmacol 65 (1979): 193-6
- Favre L, Glasson P, Vallotton MB "Reversible acute renal failure from combined triamterene and indomethacin." Ann Intern Med 96 (1982): 317-20
- Mor R, Pitlik S, Rosenfeld JB "Indomethacin- and Moduretic--induced hyperkalemia." Isr J Med Sci 19 (1983): 535-7
- Poe TE, Scott RB, Keith JF Jr "Interaction of indomethacin with furosemide." J Fam Pract 16 (1983): 610-6
- Pedrinelli R, Magagna A, Arzilli F, et al "Influence of indomethacin on the natriuretic and renin-stimulating effect of bumetanide in essential hypertension." Clin Pharmacol Ther 28 (1980): 722-31
- Kaufman J, Hamburger R, Matheson J, Flamenbaum W "Bumetanide-induced diuresis and natriuresis: effect of prostaglandin synthetase inhibition." J Clin Pharmacol 21 (1981): 663-7
- Gehr T, Sica DA, Steigler BW, Marshall C "Interaction of triamterene-hydrochlorothiazide (T-H) and ibuprofen (I)." Clin Pharmacol Ther 47 (1990): 200
- Bennett WM "Drug interactions and consequences of sodium restriction." Am J Clin Nutr 65 (1997): S678-81
- Marcy TR, Ripley TL "Aldosterone antagonists in the treatment of heart failure." Am J Health Syst Pharm 63 (2006): 49-58
- Dixey JJ, Noormohamed FH, Lant AF, Brewerton DA "The effects of naproxen and sulindac on renal function and their interaction with hydrochlorothiazide and piretanide in man." Br J Clin Pharmacol 23 (1987): 55-63
- Gurwitz JH, Everitt DE, Monane M, et al "The impact of ibuprofen on the efficacy of antihypertensive treatment with hydrochlorothiazide in elderly persons." J Gerontol A Biol Sci Med Sci 51 (1996): m74-9
- Smith DE, Brater DC, Lin ET, Benet LZ "Attenuation of furosemide's diuretic effect by indomethacin: pharmacokinetic evaluation." J Pharmacokinet Biopharm 7 (1979): 265-74
- Leary WP, Reyes AJ "Drug interactions with diuretics." S Afr Med J 65 (1984): 455-61
- Weinberg MS, Quigg RJ, Salant DJ, Bernard DB "Anuric renal failure precipitated by indomethacin and triamterene." Nephron 40 (1985): 216-8
- Ripley EB, Gehr TW, Wallace H, Wade J, Kish C, Sica DA "The effect of nonsteroidal agents (NSAIDs) on the pharmacokinetics and pharmacodynamics of metolazone." Int J Clin Pharmacol Ther 32 (1994): 12-8
- "Product Information. HydroDIURIL (hydrochlorothiazide)." Merck & Co, Inc, West Point, PA.
- Perazella MA "Drug-induced hyperkalemia: old culprits and new offenders." Am J Med 109 (2000): 307-14
- Watkins J, Abbot EC, Hensby CN, Webster J, Dollery CT "Attenuation of hypotensive effect of propranolol and thiazide diuretics by indomethacin." Br Med J 281 (1980): 702-5
- Favre L, Glasson P, Riondel A, Vallotton MB "Interaction of diuretics and non-steroidal anti-inflammatory drugs in man." Clin Sci 64 (1983): 407-15
- Ahmad S "Indomethacin-bumetanide interaction: an alert." Am J Cardiol 54 (1984): 246-7
- Heerdink ER, Leufkens HG, Herings RM, Ottervanger JP, Stricker BH, Bakker A "NSAIDs associated with increased risk of congestive heart failure in elderly patients taking diuretics." Arch Intern Med 158 (1998): 1108-12
- Furst DE "Clinically important interactions of nonsteroidal antiinflammatory drugs with other medications." J Rheumatol Suppl 17 (1988): 58-62
非专利名称: ibuprofen
品牌: Advil, Midol, Motrin, Motrin IB, Motrin Migraine Pain, Proprinal, Smart Sense Children's Ibuprofen, PediaCare Children’s Pain Reliever/Fever Reducer, PediaCare Infant’s Pain Reliever/Fever Reducer, Advil Liqui-Gels, Caldolor, NeoProfen, Genpril, Ibu, Midol IB, Children's Motrin, Motrin Junior Strength
同义词: Ibuprofen
非专利名称: hydrochlorothiazide
品牌: Aquazide H, HydroDIURIL, Microzide,
同义词: HCTZ, Hydrochlorothiazide
在药物相容性与互相作用的检测过程中使用下列的信息来源:Drugs.com, Rxlist.com, Webmd.com, Medscape.com。
- Ibuprofen Llysine-Zidovudine
- Ibuprofen Llysine-Zidovudine Capsules and Tablets
- Ibuprofen Llysine-Zidovudine Injection
- Ibuprofen Llysine-Zidovudine Intravenous
- Ibuprofen Llysine-Zidovudine Oral Solution
- Ibuprofen Llysine-Zidovudine oral/injection
- Zide-Ibuprofen lysine Intravenous
- Zide-Ibuprofen Oral Suspension
- Zide-Ibuprofen PM
- Zide-Ibuprofen Suspension
- Zide-Ibuprofen Tablets
- Zide-Ibuprofen, Phenylephrine, and Chlorpheniramine