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Mycophenolate Mofetil Oral Suspension 与 MyKidz Iron FL

Mycophenolate Mofetil Oral Suspension 与 MyKidz Iron FL互相作用以及同时服用的可能性。

检测结果:

Mycophenolate Mofetil Oral Suspension <> MyKidz Iron FL

现实性: 16.09.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

消费者信息，对这个轻微的相互作用目前不可用。一些轻微的药物相互作用可能不是临床相关的所有患者。轻微的药物相互作用通常不会造成伤害或需要改变治疗。然而，你的医疗保健提供者可以确定，如果调整到你的药物是必要的。对于临床细节，请参阅专业的相互作用的数据.

医界专家:

有限数据表明，口的生物利用度霉酚酸(MPA)可以减少伴随政府的铁制剂。该机构的相互作用尚未建立，并可用的数据是相互矛盾的。在早期的研究与七个健康的主题，管理局的1克霉酚酸酯(霉酚酸酯)与一个单一的1050毫克的剂量的持续释放硫酸亚铁(相当于210毫克铁元素)的下降意味着MPA峰等离子浓度(C)和系统暴露(AUC)通过94％和91％相比，分别到管理的霉酚酸酯单。然而，几个后续研究，包括某些进行肾移植的患者，报告没有显着变化MPA的药物动力学过合用铁在同一时间或最多四小时分开。原因的差额尚未确定。在体外，没有任何证据的配合作用之间的铁和霉酚酸酯或MPA。没有预防措施出现必要的，以避免潜在的相互作用；然而，它可能是可取的监测药物反应和血液水平密切，如果一个铁产品被添加到稳定霉酚酸酯治疗。

来源

Gelone DK, Park JM, Lake KD "Lack of an effect of oral iron administration on mycophenolic acid pharmacokinetics in stable renal transplant recipients." Pharmacotherapy 27 (2007): 1272-8
Morii M, Ueno K, Ogawa A, Kato R, Yoshimura H, Wada K, Hashimoto H, Takada M, Tanaka K, Nakatani T, Shibakawa M "Impairment of mycophenolate mofetil absorption by iron ion." Clin Pharmacol Ther 68 (2000): 613-6
"Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Mudge DW, Atcheson B, Taylor PJ, et al. "The effect of oral iron administration on mycophenolate mofetil absorption in renal transplant recipients: a randomized, controlled trial." Transplantation 77 (2004): 206-9
Lidgate D, Brandl M, Holper M, Abubakari A, Wu X "Influence of ferrous sulfate on the solubility, partition coefficient, and stability of mycophenolic acid and the ester mycophenolate mofetil." Drug Dev Ind Pharm 28 (2002): 1275-83
"Product Information. Myfortic (mycophenolic acid)." Novartis Pharmaceuticals, East Hanover, NJ.
Lorenz M, Wolzt M, Weigel G, et al. "Ferrous sulfate does not affect mycophenolic acid pharmacokinetics in kidney transplant patients." Am J Kidney Dis 43 (2004): 1098-103
Ducray PS, Banken L, Gerber M, Boutouyrie B, Zandt H "Absence of an interaction between iron and mycophenolate mofetil absorption." Br J Clin Pharmacol 62 (2006): 492-5

Mycophenolate Mofetil Oral Suspension

非专利名称: mycophenolate mofetil

品牌: Cellcept, Myfortic, MMF

同义词: Mycophenolate mofetil (oral/injection), Mycophenolate

Mycophenolate Mofetil Oral Suspension是什么？

MyKidz Iron FL

非专利名称: multivitamin with iron and fluoride

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同义词: 无

MyKidz Iron FL是什么？

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