根据名称进行药物检索

Pamprin Max 与 Rheumatrex Dose Pack Oral

Pamprin Max 与 Rheumatrex Dose Pack Oral互相作用以及同时服用的可能性。

检测结果:

Pamprin Max <> Rheumatrex Dose Pack Oral

现实性: 24.11.2022 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

谈谈你的医生之前使用的甲氨蝶呤和阿司匹林。这种组合可以增加影响的甲氨蝶呤在你的身体。这种组合可能会导致恶心、呕吐、腹泻,喉咙痛，发冷、发烧、皮疹、不寻常的瘀伤或流血的,苍白的皮肤,黑色的尿液肿的肢体，或是呼吸短促。如果你采取这两种药物在一起，告诉医生，如果你有任何的这些症状。你可能需要的剂量调整或特别的测试，如果你采取这两种药物。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

一般避免：水杨酸可能会干扰的肾消除甲氨蝶呤和可以取代它从结合的网站。在药理作用和毒性的甲氨蝶呤可能会增加。患者接受高剂量甲氨蝶呤的风险更大的发展中的毒性。

管理：如果这些试剂的使用必须同时，应谨慎行事，以及患者应密切监测为的迹象和症状的骨髓抑制和肾毒性。患者应报告可能出现的症状的毒性，包括恶心、呕吐、腹泻、性口炎、喉咙疼痛、发冷、发烧、皮疹、不寻常的瘀伤或出血、黄疸病、尿、肿胀的肢体，或是呼吸短促，他们的医生。病人也应该建议，以避免任何其他的柜台水杨酸产品。

来源

Dixon RL, Henderson ES, Rall DP "Plasma protein binding of methotrexate and its displacement by various drugs." Fed Proc 24 (1965): 454
Ellison NM, Servi RJ "Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration." Cancer Treat Rep 69 (1985): 342-3
Singh RR, Malaviya AN, Pandey JN, Guleria JS "Fatal interaction between methotrexate and naproxen." Lancet 1 (1986): 1390
"Product Information. Methotrexate (methotrexate)." Lederle Laboratories, Wayne, NJ.
Taylor JR, Halprin KM "Effect of sodium salicylate and indomethacin on methotrexate-serum albumin binding." Arch Dermatol 113 (1977): 588-91
Kraus A, Alarcon-Segovia D "Low dose MTX and NSAID induced "mild" renal insufficiency and severe neutropenia." J Rheumatol 18 (1991): 1274
Baker H "Intermittent high dose oral methotrexate therapy in psoriasis." Br J Dermatol 82 (1970): 65-9
Tracy TS, Krohn K, Jones DR, Bradley JD, Hall SD, Brater DC "The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis." Eur J Clin Pharmacol 42 (1992): 121-5
Maiche AG "Acute renal failure due to concomitant action of methotrexate and indomethacin." Lancet 1 (1986): 1390
Stewart CF, Fleming RA, Germain BF, et al "Aspirin alters methotrexate disposition in rheumatoid arthritis patients." Arthritis Rheum 34 (1991): 1514-20
Liegler DG, Henderson ES, Hahn MA, Oliverio VT "The effect of organic acids on renal clearance of methotrexate in man." Clin Pharmacol Ther 10 (1969): 849-57
Stewart CF, Fleming RA, Arkin CR, Evans WE "Coadministration of naproxen and low-dose methotrexate in patients with rheumatoid arthritis." Clin Pharmacol Ther 47 (1990): 540-6
Skeith KJ, Russell AS, Jamali F, Coates J, Friedman H "Lack of significant interaction between low dose methotrexate and ibuprofen or flurbiprofen in patients with arthritis." J Rheumatol 17 (1990): 1008-10
Frenia ML, Long KS "Methotrexate and nonsteroidal antiinflamatory drug interactions." Ann Pharmacother 26 (1992): 234-7
Dupuis LL, Koren G, Shore A, Silverman ED, Laxer RM "Methotrexate-nonsteroidal antiinflammatory drug interaction in children with arthritis." J Rheumatol 17 (1990): 1469-73
Mandel MA "The synergistic effect of salicylates on methotrexate toxicity." Plast Reconstr Surg 57 (1976): 733-7

Pamprin Max

非专利名称: acetaminophen / aspirin / caffeine

品牌: Anacin Advanced Headache Formula, Arthriten, Backaid IPF, Excedrin, Goodys Extra Strength, Goody's Headache Powders, Pain Reliever Plus, Pamprin Max, Uricalm Intensive, Genace, Excedrin Geltab, Supac, Excedrin Migraine, Excedrin Extra Strength, Excedrin Extra Strength Geltab, Excedrin Migraine Geltab, Excedrin Express, Excedrin Menstrual Express, Bayer Migraine Formula, Goodys Headache Powders, Vanquish

同义词: 无

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