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Proquin XR 与 Theophylline Oral Solution

Proquin XR 与 Theophylline Oral Solution互相作用以及同时服用的可能性。

检测结果:

Proquin XR <> Theophylline Oral Solution

现实性: 02.11.2023 评论家: 医学副博士Shkutko P.M., in

在该服务的官方手册中，已注明相关研究结果统计规定的互相作用。该互相作用或对患者健康引起不良后果，或起到良好效果。具体联合用药问题，需遵从医嘱。

用户:

环丙沙星的可能显着增加，血液水平的茶碱，这可能导致潜在的严重和危及生命的副作用。谈谈你的医生如果你有任何疑问或关切的问题。你的医生可以规定替代品，不进行互动，或者可能需要一剂量的调整或更频繁的监测通过你的医生到安全地使用这两种药物。联系您的医生如果您开发恶心、呕吐、腹泻、食欲丧失、头痛、震颤、混乱、烦躁、失眠症，癫痫发作，心悸，和/或心跳不规则，因为这些可能的迹象和症状的过茶碱水平。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

一般避免：共同给予与环丙沙星的可能显着增加，血清浓度的茶碱和相关风险的毒性。该机构是环丙沙星的抑制作用的茶碱的新陈代谢通过CYP450 1A2. 情况报告和药物代谢动力学的研究表明，环丙沙星500毫克到750毫克每天两次可以减少清关的茶碱通过大约20％至65％，导致有毒茶碱水平和/或临床毒性在一些患者。高达四倍增加在茶碱的血清水平已有报道，发现的毒性的临床作为早期两到三天，通常在一个星期内发起的环丙沙星。然而，相互作用受到高度interpatient可变性和不一致地产生显着临床的药物动力学的变化。严重和严厉的反应已经包括心脏的逮捕、扣押、持续状态、呼吸衰竭、甚至死亡。缉获量也可能发生在缺乏有毒茶碱水平由于添加剂抑制性的效果的环丙沙星和茶碱在γ-氨基丁酸(GABA)受体的网站。因为老年患者和患有慢性阻塞性肺部疾病、充血性心力衰竭，或肝硬化通常具有较低的茶碱清除率方面，它们可能特别容易受到茶碱性毒性。茶碱似乎并不改变药物代谢动力学的环丙沙星和其他种药物.

管理：在使用的茶碱或其盐类组合与环丙沙星一般应当是可以避免的。如果合用是必需的，茶碱的剂量，可能需要将减少。药物反应和血清水平应该密切监督下开始、停止或更改的剂量的环丙沙星、和茶碱量进行相应的调整。患者应该建议联系他们的医生如果他们的经验的迹象和症状暗示的茶碱性毒性，如恶心、呕吐、腹泻、厌食症、头痛、震颤、烦躁、迷惑、失眠、扣押、心悸，心律失常。另一种药物，包括吉米沙星、左氧氟沙星、莫西沙星、和氧氟沙星已报告导致轻微或没有变化茶碱水平通常推荐剂量和可能更安全的替代品在茶碱-治疗的患者。

来源

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Proquin XR

非专利名称: ciprofloxacin

品牌: Cipro, Cipro XR, Proquin XR, Cipro IV

同义词: 无

Proquin XR是什么？

Theophylline Oral Solution

非专利名称: theophylline

品牌: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

同义词: Theophylline

Theophylline Oral Solution是什么？

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